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1.
Rev Neurol ; 53(12): 729-34, 2011 Dec 16.
Artigo em Espanhol | MEDLINE | ID: mdl-22127659

RESUMO

AIM: To evaluate the effectiveness and safety of infiltrating the psoas muscle with botulinum toxin guided by computerised tomography (CT) in order to reduce dynamic contracture in bending the hip. PATIENTS AND METHODS: The study involves a series of five children diagnosed with spastic cerebral palsy and bilateral involvement. All the children were able to walk and they presented an attitude on bending the hips and knees consisting in the typical 'crouch gait' together with a dynamic contracture of the hips and knees. They did not present any contraindications for the use of botulinum toxin and their parents gave their consent. Under CT control and anaesthetic sedation, both psoas muscles were infiltrated with a dose of 3 U/kg of body weight; later, both ischiotibial muscles were infiltrated using 3 U/kg doses. The patients were evaluated both prior to and four weeks after infiltration; the muscular range was assessed by means of goniometry, muscular tone was evaluated using the modified Ashworth scale, spasticity was measured using Tardieu's dynamic test and the attitude in bending the hips and knees under a load was assessed by goniometric measurement. Likewise, adverse secondary effects to the puncture or to the use of the toxin were recorded. RESULTS: The five patients reported an improvement in both mobility (with a reduction of tone and contracture) and the posture when standing. CONCLUSIONS: Infiltration of the psoas muscle guided by CT is an effective, safe technique for reducing spasticity in bending the hip, which, if accompanied by infiltration of the ischiotibial muscles, improves the attitude on bending the hip and knee.


Assuntos
Toxinas Botulínicas Tipo A , Paralisia Cerebral/tratamento farmacológico , Fármacos Neuromusculares , Músculos Psoas/efeitos dos fármacos , Músculos Psoas/fisiopatologia , Tomografia Computadorizada por Raios X/métodos , Toxinas Botulínicas Tipo A/farmacologia , Toxinas Botulínicas Tipo A/uso terapêutico , Paralisia Cerebral/fisiopatologia , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Fármacos Neuromusculares/farmacologia , Fármacos Neuromusculares/uso terapêutico , Resultado do Tratamento
2.
Rev. neurol. (Ed. impr.) ; 53(12): 729-734, 16 dic., 2011. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-97983

RESUMO

Objetivo. Evaluar la eficacia y seguridad de la infiltración del psoas con toxina botulínica guiada por tomografía axial computarizada (TAC) en la reducción de la contractura dinámica en la flexión de la cadera. Pacientes y métodos. Serie de cinco niños diagnosticados de parálisis cerebral espástica y afectación bilateral. Todos los niños eran ambulantes, presentaban una actitud en la flexión de las caderas y rodillas con la típica ‘marcha agazapada’, una contractura dinámica de caderas y rodillas, no presentaban contraindicaciones para el uso de toxina botulínica, y sus padres dieron su consentimiento. Bajo control de TAC y sedación anestésica, se infiltraron ambos psoas con una dosis de 3 U/kg de peso; posteriormente, se infiltraron ambos isquiotibiales en dosis de 3 U/kg. Los pacientes fueron evaluados previamente y cuatro semanas después de la infiltración, valorándose el rango muscular mediante goniometría, el tono muscular mediante la escala modificada de Ashworth, la espasticidad mediante el test dinámico de Tardieu, y la actitud en la flexión de las caderas y rodillas en carga mediante medición goniométrica. Igualmente, se registraron efectos adversos secundarios a la punción o al uso de la toxina. Resultados. En los cinco pacientes se produjo una mejora de la movilidad, y una disminución del tono y la contractura, así como de la postura en bipedestación. Conclusiones. La infiltración del psoas guiada por TAC es una técnica efectiva y segura para disminuir la espasticidad en la flexión de la cadera, que, acompañada de la infiltración de los isquiotibiales, mejora la actitud en la flexión de cadera y rodilla (AU)


Aim. To evaluate the effectiveness and safety of infiltrating the psoas muscle with botulinum toxin guided by computerised tomography (CT) in order to reduce dynamic contracture in bending the hip. Patients and methods. The study involves a series of five children diagnosed with spastic cerebral palsy and bilateral involvement. All the children were able to walk and they presented an attitude on bending the hips and knees consisting in the typical ‘crouch gait’ together with a dynamic contracture of the hips and knees. They did not present any contraindications for the use of botulinum toxin and their parents gave their consent. Under CT control and anaesthetic sedation, both psoas muscles were infiltrated with a dose of 3 U/kg of body weight; later, both ischiotibial muscles were infiltrated using 3 U/kg doses. The patients were evaluated both prior to and four weeks after infiltration; the muscular range was assessed by means of goniometry, muscular tone was evaluated using the modified Ashworth scale, spasticity was measured using Tardieu’s dynamic test and the attitude in bending the hips and knees under a load was assessed by goniometric measurement. Likewise, adverse secondary effects to the puncture or to the use of the toxin were recorded. Results. The five patients reported an improvement in both mobility (with a reduction of tone and contracture) and the posture when standing. Conclusions. Infiltration of the psoas muscle guided by CT is an effective, safe technique for reducing spasticity in bending the hip, which, if accompanied by infiltration of the ischiotibial muscles, improves the attitude on bending the hip and knee (AU)


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Músculos Psoas , Espasticidade Muscular/tratamento farmacológico , Toxinas Botulínicas Tipo A/farmacocinética , Tomografia Computadorizada por Raios X , Paralisia Cerebral/tratamento farmacológico , Contratura de Quadril/tratamento farmacológico
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